Disinhibition of RVLM neural circuits and regulation of sympathetic nerve discharge at peak hyperthermia
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چکیده
منابع مشابه
Disinhibition of RVLM neural circuits and regulation of sympathetic nerve discharge at peak hyperthermia.
Hyperthermia is a potent activator of visceral sympathetic nerve discharge (SND), and the functional integrity of the rostral ventral lateral medulla (RVLM) is critically important for sustaining sympathoexcitation at peak hyperthermia. However, RVLM mechanisms mediating SND activation to acute heat stress are not well understood. Because RVLM GABA is tonically inhibitory to sympathetic nerve o...
متن کاملInhibition of RVLM synaptic activation at peak hyperthermia reduces visceral sympathetic nerve discharge.
Hyperthermia is an environmental stressor that produces marked increases in visceral sympathetic nerve discharge (SND) in young rats. The brainstem in rats contains the essential neural circuitry for mediating visceral sympathetic activation; however, specific brainstem sites involved remain virtually unknown. The rostral ventral lateral medulla (RVLM) is a key central nervous system region inv...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2013
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00494.2013